Population research in anthropogenetics
Abstract
The article highlights that researchers studying human heredity inevitably encounter issues of population genetics and the necessity of conducting calculations. It is noted that most studies in the field of anthropogenetics aim to identify genetic markers of phenotypic traits. Examples of the most common errors in organizing research on human heredity are provided, including the incorrect use of the term “population”. These mistakes occur at the initial stage of research during group formation and lead to inaccurate results. The article emphasizes that the root cause of such errors is the lack of a national scientific school of population genetics. It explains why a proper study of human genetics requires considering a population's history, culture, demographic composition, and structure. An action algorithm for calculating the inbreeding index as a population criterion is presented. Attention is drawn to carefully considering the ethnic and geographic origins of study participants when forming research groups. The article underscores that an essential component of population studies in anthropogenetics is the determination of heritability indices.
References
Utevskaya O. M., Atramentova L. A. Heritability of Reproductive Traits in the Medicinal Leech Hirudo medicinalis L. Genetika. 2002. Vol. 38(1). P. 44–49. https://doi.org/10.1023/A:1013711710927.
Boiko O. D. Istoriia Ukrainy. Kyiv : Akademvydav. 2018. 720 p. [in Ukrainian]
Segeda S. P. Antropolohiia : navch. posibnyk. Kyiv : Lybid', 2001. 336 p. [in Ukrainian]
Utevska O. M., Pshenichnov A. S., Dibirova Kh. D. et al. Gene Pool Similarities and Differences between Ukrainians and Russians of Slobozhanshchina Based on Y-Chromosome Data. Cytology and Genetics. 2015. Vol. 49(4). P. 245–253. https://doi.org/10.3103/S0095452715040106
Atramentova L. O., Utevska O. M. Estimation of the population frequency of age-dependent multifactorial diseases. Factors of experimental evolution of organisms. 2021. Vol. 29. P. 137–141. https://doi.org/10.7124/FEEO.v29.1420.
Cavalli-Sforza L. L., Bodmer W. F. The genetics of human populations. W. H. Freeman. San Francisco, 1971. 965 p. https://doi.org/10.1002/ajpa.1330390117.
Atramentova L. A., Filiptsova O. V., Mukhin V. N., Osipenko S. Y. Genetic demography of Ukrainian urban populations in the 1990s: ethnic geographic characteristics of migration in the Donetsk population. Genetika. 2002. Vol. 38. P. 1189–1195.
Atramentova L. A., Filiptsova O. V., Mukhin V. N. Genetic demographic processes in Ukrainian urban populations in the 1990s: the marriage structure of the Donetsk population. Genetika. 2000. Vol. 36(1). P. 81–87. https://doi.org/10.1023/A:1020609006063.
Atramentova L. A., Filiptsova O. V., Osipenko S. Y. Genetic demography of Ukrainian urban populations in the 1990s: Ethnicity and birthplaces of migrants to the Poltava population. Genetika. 2002. Vol. 38. P. 1082–1087.
Atramentova L. A., Meshcheryakova I. P. Genetic demographic parameters of the marriage structure of the Yevpatoria population. Genetika. 2007. Vol. 43. P. 315–322. https://doi.org/10.1134/S1022795407030143.
Spuhler J. N. Assortative mating with respect to physical characteristics. Eugenics Quart. 1968. Vol. 15(2). P. 128–140.
Li Ching Chun An introduction to population genetics. National Peking University Press, 1948. 321 p.