Influence of various factors on the antiradical activity of Panax ginseng С. A. Meyer extracts

  • V. N. Reshetnikov
  • H. G. Shutava
  • S. N. Shysh
  • T. V. Gil


Aim. The aim of the work was to evaluate the anti-radical activity of extracts of ginseng's underground and overground organs Panax ginseng C.A. Mey, depending on various factors – age of plants, collection time and cultivation conditions. Methods. Extracts obtained from various plant organs were evaluated in the model system with cation-radicals ABTS. At the same time, the amount of extractive substances and phenolic compounds was determined. Results. Samples of leaves and roots of ginseng of 1, 2, 3, 5, 9 years of vegetation from the collection of the Central Botanical Garden of the National Academy of Sciences of Belarus were analyzed. It is established that extracts of ginseng leaves of P. ginseng can be considered as sufficiently effective anti-radical agents. Anti-radical activity of extracts of roots and leaves of ginseng differed significantly depending on the weather conditions of the growing season. Conclusions. It is shown that extracts of ginseng leaves differ by the maximum antiradical activity. Extracts of ginseng roots showed a much lower anti-radical activity in comparison with leaf extracts, which may be due to both a smaller amount of extractives extracted from water-ethanol extraction and their composition.

Keywords: ginseng, antiradical activity, phenolic compounds, extractives.


Holubeva V.S., Romanchuk V.A., Hyl′ T.V. Influence of sowing density on the quality of seedlings Panax ginseng C.A. Meu. Theoretical and applied aspects of plant introduction as a prospective direction for the development of science and the national economy: proceedings of the International Scientific Conference dedicated to the 75th anniversary of the foundation of the CBG of the National Academy of Sciences of Belarus (Mynsk, 12–15 July 2007). Minsk: Edyt VV, 2007. Vol. 1. P. 136–138.

Anoshenko B.I͡u., Kukhareva L.V. Perspectives of medicinal and spicy aromatic plant growing. Science and innovation. 2014. P. 15–17.

Jia Liu, Yang Liu, Long Zhao, Zhong-Hua Zhang, Zhon-Hua Tang. Profiling of ginsenosides in the two medicinal Panax herbs based on ultra-performance liquid chromatography-electrospray ionization-mass spectrometry. Springerplus. 2016. No. 5 (1). P. 1770.

Keum Y.S., Park K.K., Lee J.M., Chun K.S., Park J.H., Lee S.K., Kwon H., Surh Y.J. Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng. Cancer Lett. 2000. Vol. 150. P. 41–48.

Popov A.M. Mechanisms of biological activity of glycosides of ginseng: comparison with glycosides of holothurians Vestnik of the Far East Branch of the Russian Academy of Sciences, 2006. No. 6. P. 92–104.

Leung K.W., Wong A.S. Pharmacology of ginsenosides: a literature. Chin Med. 2010. Vol. 5. P. 20.

Joint system of environmental information. National Statistical Committee of the Republic of Belarus. URL: (Last accessed: 27.02.2018).

Re R., Pellegrini N., Proteggente A., Pannala A., Yang M., Rice-Evans C. Antioxidant activity applying an improved ABTS radical cationdecolorization assay. Free Radical Biology and Medicine. 1999. Vol. 26. P. 1231–1237.

Ikawa M., Schaper T.D., Dollard C.A., Sasner J.J. Utilization of Folin-Ciocalteu Phenol Reagent for the Detection of Certain Nitrogen Compounds. J. Agric. Food Chem. 2003. Vol. 51. P. 1811–1813.

State Pharmacopoeia of the Republic of Belarus. In 2 volumes. Minsk, 2012. Vol. 1. C. 406.